I have apache setup with:

DirectoryIndex index.jsp

I have mod_jk2 setup with:

[uri:/*.jsp]

The result is requests for index.jsp or for a directory with an index.jsp are
properly forwarded to tomcat, however if I request a directory with no index.jsp
file in that I want to have mod_autoindex handle, then mod_jk2 still forwards
that to tomcat which returns an error because there is no index file.

There needs to be support for forwarding using handlers, which would allow you
to properly configure a Files directive to handle them with a SetHandler. 
Apache should be the one to figure out if the file exists.  Another symptom of
this same problem is requesting /foo.jsp where foo.jsp doesn't exist.  Apache
should be the one returning a 404, not tomcat.

I want Apache to be the one deciding what should be handled when I am using its
configuration directives.  Using Location-style directives is a horrible idea
for such things as it is a security issue when you have various names that can
refer to the same file, eg. Windows.  As the Apache documentation clearly
states, Location directives should not be used to control access to files on
disk but should only be used for true virtual namespaces.